Characterization of an Emergent Chicken H3N8 Influenza Virus in Southern China: a Potential Threat to Public Health

Author:

Chen Peiwen123,Jin Ziying23,Peng Liuxia1,Zheng Zuoyi1,Cheung Yiu-Man24,Guan Jing13,Chen Liming15,Huang Yiteng15,Fan Xiaohui6,Zhang Zengfeng6,Shi Dongmei3,Xie Jin3,Chen Rirong1,Xiao Boheng1,Yip Chun Hung234,Smith David K.124,Hong Wenshan1,Liu Yongmei2,Li Lifeng1234,Wang Jia123,Holmes Edward C.47ORCID,Lam Tommy Tsan-Yuk1234,Zhu Huachen1234,Guan Yi1234ORCID

Affiliation:

1. Guangdong-Hong Kong Joint Laboratory of Emerging Infectious Diseases, Joint Institute of Virology (STU/HKU), Shantou University, Shantou, Guangdong, China

2. State Key Laboratory of Emerging Infectious Diseases (SKLEID), School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China

3. Advanced Pathogen Research Institute, Shenzhen, Guangdong, China

4. Laboratory of Data Discovery for Health Limited, Hong Kong SAR, China

5. The First Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, China

6. Department of Microbiology, Guangxi Medical University, Nanning, Guangxi, China

7. Sydney Institute for Infectious Diseases, School of Medical Sciences, University of Sydney, Sydney, New South Wales, Australia

Abstract

A novel H3N8 virus with demonstrated zoonotic potential has emerged and disseminated in chickens in China. It was generated by reassortment between avian H3 and N8 virus(es) and long-term enzootic H9N2 viruses present in southern China.

Funder

HHS | National Institutes of Health

Li Ka Shing Foundation

Shenzhen-Hong Kong Science and Technology Cooperation Zone

MOST | National Natural Science Foundation of China

Innovation and Technology Commission

Ministry of Science and Technology of Guangdong, China

Ministry of Science and Technology of Shantou, China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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