Fungicidal activity of cecropin A

Author:

DeLucca A J1,Bland J M1,Jacks T J1,Grimm C1,Cleveland T E1,Walsh T J1

Affiliation:

1. Southern Regional Research Center, U.S. Department of Agriculture, New Orleans, Louisiana 70124, USA.

Abstract

Cecropin A (CA) fungicidal properties were explored. Nongerminated and germinated Aspergillus spp. and Fusarium spp. conidia were treated with CA. CA achieved complete lethality at < or = 25 microM (99 micrograms/ml) for germinating, but not nongerminating, conidia of Aspergillus spp. CA achieved total lethality for nongerminated and germinating conidia of Fusarium spp at 1.5 microM (6 micrograms/ml). MIC and minimal lethal concentration assays in buffered RPMI medium gave similar results.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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