Resistance of Salmonellae Isolated in 1959 and 1960 to Tetracyclines and Chloramphenicol

Author:

Ramsey Carolyn H.1,Edwards P. R.1

Affiliation:

1. Communicable Disease Center, U. S. Public Health Service, Department of Health, Education, and Welfare, Atlanta, Georgia

Abstract

The resistance of cultures of Salmonella typhimurium to tetracyclines and chloramphenicol has been examined periodically. Although none of 200 cultures isolated prior to 1948 was resistant to the antibiotics, 5% of 100 cultures from man and 9% of 100 cultures from fowls which were isolated in 1956 and 1957 were resistant to tetracyclines. Among 158 cultures isolated from man and 100 cultures isolated from fowls in 1959 and 1960, 13.9 and 29%, respectively, were resistant to tetracyclines. In the last series, cultures resistant to chloramphenicol were found for the first time. Among 150 cultures of other Salmonella serotypes from man and 137 similar cultures isolated from fowls in 1959 and 1960, 5.3 and 8%, respectively, were found resistant to tetracyclines. There is no obvious explanation for the higher percentage of resistant strains occurring in S. typhimurium than in other serotypes.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference10 articles.

1. Salmonellae and shigellae in a group of rural South Africal Bantu school shildren;BOKKENHEUSER V.;J. Hyg.,1960

2. BUTrIAUX R. P. NICOLLE L. LEMINOR AND B. GAUDIER. 1956. Etude Epidemiologique des Gastro-enterites a Escherichia coli dans un Service Hospitalier du Nord de la France. Arch. maladies app. digest. et maladies nutrition 45:225-247.

3. Clinical and microbiological aspects of salmonellosis;EISENBERG G. M.;Am. J. Med. Sci.,1958

4. Resistance of Salmonella typhimurium to tetracyclines;HUEY C. R.;Proc. Soc. Exptl. Biol. Med.,1958

5. The sensitivity of Salmonella species to synnematin B, chloramphenicol, and tetracyclines;JOACHIN A.;Antibiotics & Chemotherapy,1959

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