Lack of Interference of Guanosine with Ribavirin Aerosol Treatment of Influenza A Infection in Mice-Reference-Cited by-同舟云学术

Lack of Interference of Guanosine with Ribavirin Aerosol Treatment of Influenza A Infection in Mice

Published:1981-10 Issue:4 Volume:20 Page:477-480
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Knight Vernon¹,Wilson Samuel Z.¹,Alling David W.²,Moore Rebecca V.¹,Longoria Rose M.¹

Affiliation:

1. Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas 77030

2. National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20205

Abstract

Guanosine or guanosine 5′-monophosphate did not reduce the protective effect of ribavirin aerosol in influenza virus A/Aichi/68 H3N2 infection of mice. Both compounds partially interfered with the action of a wide range of ribavirin concentrations against influenza virus A/WSN replication in cell culture.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.20.4.477

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5. Inhibition of influenza RNA syn- thesis by Virazole (ribavirin);Scholtissek C.;Arch. Virol.,1976

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