Affiliation:
1. Department of Parasitology, Claude Bernard University, Lyon, France.
Abstract
Isoprinosine was given at daily doses of 0.5, 1, 2, and 4 g kg-1 of body weight to jirds that were infected for 3 months with Echinococcus multilocularis metacestodes. The effects of the different drug doses on metacestodes were studied by transmission electron microscopy and biochemical methods. At lower doses, increases in uric acid and adenosine deaminase activity were noted. At 4 g kg-1 of body weight, marked ultrastructural damage with metabolic perturbations was observed.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference19 articles.
1. Barrett J. 1981. Catabolism and energy production p. 72-109. In Biochemistry of parasitic helminths. Macmillan Publishers Ltd. London.
2. Assay of proteins in the presence of interfering materials;Bensadoun A.;Anal. Biochem.,1976
3. The use of adenosine deaminase assays in the diagnosis of tuberculosis;Blake J.;S. Afr. Med. J.,1982
4. Multicentre clinical trials of benzimidazole-carbamates in human cystic echinococcosis (phase 2);Davis A.;Bull. W. H. O.,1989
5. Multicentre trials of benzimidazole carbamate in human echinococcosis;Davis A.;Bull. W. H. O.,1986
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