Paracoccidioides brasiliensis-stimulated human gamma/delta T cells support antibody production by B cells-Reference-Cited by-同舟云学术

Paracoccidioides brasiliensis-stimulated human gamma/delta T cells support antibody production by B cells

Published:1995-04 Issue:4 Volume:63 Page:1608-1610
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Munk M E¹,Fazioli R A¹,Calich V L¹,Kaufmann S H¹

Affiliation:

1. Department of Immunology, University of Ulm, Germany.

Abstract

Paracoccidioidomycosis patients show hyperactive humoral immune responses. Consequently, we investigated whether cytokines in supernatants from Paracoccidioides brasiliensis-stimulated gamma/delta T cells support B-cell activation. We detected proliferation of B cells and increased immunoglobulin M (IgM) and IgG production. Thus, gamma/delta T cells may participate in polyclonal B-cell activation during paracoccidioidomycosis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.63.4.1608-1610.1995

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