Evaluation of the Performance and Clinical Impact of a Rapid Phenotypic Susceptibility Testing Method Directly from Positive Blood Culture at a Pediatric Hospital-Reference-Cited by-同舟云学术

Evaluation of the Performance and Clinical Impact of a Rapid Phenotypic Susceptibility Testing Method Directly from Positive Blood Culture at a Pediatric Hospital

Published:2022-08-17 Issue:8 Volume:60 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Truong Thao T.¹^ORCID,Mongkolrattanothai Kanokporn²³,Flores Irvin Ibarra¹,Dien Bard Jennifer¹³^ORCID

Affiliation:

1. Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, Los Angeles, California, USA

2. Department of Pediatrics, Division of Infectious Diseases, Children’s Hospital Los Angeles, Los Angeles, California, USA

3. Keck School of Medicine, University of Southern California, Los Angeles, California, USA

Abstract

Bloodstream infection poses a significant medical emergency that necessitates timely administration of appropriate antibiotics. Standard laboratory workup for antimicrobial susceptibility testing (AST) involves subculture of organisms from positive blood bottles followed by testing using broth microdilution; however, this process can take several days.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/jcm.00122-22

Reference24 articles.

1. Long-term morbidity and mortality following bloodstream infection: A systematic literature review

2. Initiation of Inappropriate Antimicrobial Therapy Results in a Fivefold Reduction of Survival in Human Septic Shock

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