Affiliation:
1. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322
Abstract
ABSTRACT
When thymidylate production is diminished by a mutation affecting dCTP deaminase,
Escherichia coli
is known to use an alternate pathway involving deoxycytidine as an intermediate. The pathway requires the gene for any of three nucleoside diphosphate kinases (
ndk
,
pykA
, or
pykF
) and the gene for a 5′-nucleotidase (
yfbR
).
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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