Time Series Transcriptomic Analysis of Bronchoalveolar Lavage Cells from Piglets Infected with Virulent or Low-Virulent Porcine Reproductive and Respiratory Syndrome Virus 1-Reference-Cited by-同舟云学术

Time Series Transcriptomic Analysis of Bronchoalveolar Lavage Cells from Piglets Infected with Virulent or Low-Virulent Porcine Reproductive and Respiratory Syndrome Virus 1

Published:2022-02-09 Issue:3 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Sánchez-Carvajal J. M.¹^ORCID,Rodríguez-Gómez I. M.¹^ORCID,Ruedas-Torres I.¹,Zaldívar-López S.²,Larenas-Muñoz F.¹,Bautista-Moreno R.³,Garrido J. J.²,Pallarés F. J.¹,Carrasco L.¹,Gómez-Laguna J.¹

Affiliation:

1. Department of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain

2. Department of Genetics, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain

3. Andalusian Platform of Bioinformatic, University of Málaga, Campanillas, Málaga, Spain

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the major threats to swine health and global production, causing substantial economic losses. We explore the mechanisms involved in the modulation of host immune response at lung level performing a time-series transcriptomic analysis upon experimental infection with two PRRSV-1 strains of different virulence.

Funder

Spanish Ministry of Economy and Competitiveness

Spanish Minitry of Economy and Competitiveness

University of Córdoba

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01140-21

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