Abstract
The cell surface antigens of Escherichia coli B were investigated. We found that mice immunized with live bacteria responded with an immune response directed mainly against the protein structure of the cell surface. The lipopolysaccharide component of the bacterium was immunogenic, but its contribution to the overall response was only secondary. It is suggested that when considering the immune response to gram-negative bacteria, more attention should be given to the protein antigens.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference9 articles.
1. Sur les determinants dommuns des;Barber C.;Enterobacteriaceae. Pathol. Microbiol.,1968
2. Reaginic antibody production to protein antigens of Escherichia coli and Pseudomonas aeruginosa by mice;Danneman P. J.;Infect. Immun.,1976
3. Colorimetric method for deternmination of sugars and related substances;Dubois M.;Anal. Chem.,1956
4. Immunological studies of an antigen common to many gram-negative bacteria with special reference to E. coli;Kaijser B.;Int. Arch. Allergy Appl. Immunol.,1975
5. Kass E. H. and S. M. Wolff. 1973. Bacterial lipopolysaccharides. The University of Chicago Press Chicago.
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献