Phagocytosis and killing of Pseudomonas aeruginosa by mouse polymorphonuclear leukocytes in vitro promoted by antiserum to the slime glycolipoprotein

Author:

Bishop O,Orr T,Bartell P F

Abstract

The resistance of Pseudomonas aeruginosa to phagocytosis by polymorphonuclear leukocytes was overcome by opsonization with antibody to slime glycolipoprotein or, to a lesser extent, with complement. Resistance was most effectively overcome in the presence of both. Protection against viable-cell challenge conferred by anti-glycolipoprotein serum in experimental infection is discussed briefly in the light of these findings.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Polysaccharide Antigens ofPseudomonas Aeruginosa;Critical Reviews in Microbiology;1990-01

2. Protective Effect of a Traditional Chinese Medicine, Xiao-Chai-Hu-Tang (Japanese Name:Shosaiko-To), OnPseudomonas AeruginosaInfection in Mice;Immunopharmacology and Immunotoxicology;1987-01

3. An Electron Microscopic Study of Pathogenesis of Urinary Tract Infection Caused by Pseudomonas aeruginosa P 9 in Mice;Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology;1985-11

4. In vitro effect of the slime of Pseudomonas aeruginosa on the function of human polymorphonuclear neutrophils;Infection and Immunity;1984-06

5. Phagocyte—Pathogenic Microbe Interactions;International Review of Cytology;1983

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