Nipah Virus Infection

Author:

Ang Brenda S. P.123,Lim Tchoyoson C. C.45,Wang Linfa67ORCID

Affiliation:

1. Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore

2. Lee Kong Chian School of Medicine, Singapore

3. National University of Singapore, Singapore

4. Department of Neuroradiology, National Neuroscience Institute, Singapore

5. Duke-NUS Medical School, Singapore

6. Programme in Emerging Infectious Disease, Duke-NUS Medical School, Singapore

7. Duke Global Health Institute, Duke University, Durham, North Carolina, USA

Abstract

ABSTRACT Nipah virus, a paramyxovirus related to Hendra virus, first emerged in Malaysia in 1998. Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbreak, transmission occurred primarily through contact with pigs, whereas in Bangladesh and India, it is associated with ingestion of contaminated date palm sap and human-to-human transmission. Bats are the main reservoir for this virus, which can cause disease in humans and animals. There are currently no effective therapeutics, and supportive care and prevention are the mainstays of management.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference47 articles.

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4. Japanese encephalitis virus encephalitis: an overview;Thongcharoen P;Southeast Asian J Trop Med Public Health,1989

5. Lessons from the Nipah virus outbreak in Malaysia;Looi LM;Malays J Pathol,2007

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