High Rate of Intestinal Colonization with Extended-Spectrum-β-Lactamase-Producing Organisms in Household Contacts of Infected Community Patients

Author:

Valverde Aránzazu12,Grill Fabio3,Coque Teresa M.12,Pintado Vicente3,Baquero Fernando12,Cantón Rafael12,Cobo Javier3

Affiliation:

1. Servicio de Microbiología

2. CIBER en Epidemiología y Salud Pública (CIBERESP)

3. Servicio de Enfermedades Infecciosas, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain

Abstract

ABSTRACT Fecal carriage of extended-spectrum-β-lactamase (ESBL)-producing organisms was detected in 70% of index cases of patients ( n = 40) with community-acquired infections due to ESBL producers and reached 16.7% in household contacts ( n = 54). A total of 66% of ESBL-producing organisms from index cases were indistinguishable from isolates from household contacts by pulsed-field gel electrophoresis. Patients with community infections and members of their households represent a reservoir for ESBL producers, increasing dispersal of resistance in healthy people.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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