Affiliation:
1. Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8673, Japan
Abstract
ABSTRACT
Including type strains, mitochondrial cytochrome
b
genes of 32 strains of
Candida albicans
and 6 strains of
Candida stellatoidea
, presently treated as a synonym for
C. albicans
, were partially sequenced. Analysis of 396-bp nucleotide sequences of the strains under investigation divided
C. albicans
isolates into three types: type I, type II, and type III; however, strains of
C. stellatoidea
represented distinct type IV isolates. Deduced amino acid sequences of type I, type II, and type III were identical and differed from that of type IV by one amino acid. Genotypes (rDNA type) of the test strains were also checked. Cytochrome
b
typing did not correlate with genotyping, and different genotypes occurred for one cytochrome
b
type. This study shows that cytochrome
b
gene sequences are useful for analyzing the genetic relatedness of
C. albicans
isolates and effective for differentiating
C. stellatoidea
from
C. albicans
.
Publisher
American Society for Microbiology
Cited by
14 articles.
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