Serological Detection of Capillaria hepatica by Indirect Immunofluorescence Assay-Reference-Cited by-同舟云学术

Serological Detection of Capillaria hepatica by Indirect Immunofluorescence Assay

Published:2000-01 Issue:1 Volume:38 Page:431-433
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Juncker-Voss Martina¹,Prosl Heinrich¹,Lussy Helga²,Enzenberg Ulrike³,Auer Herbert⁴,Nowotny Norbert²

Affiliation:

1. Institute of Parasitology and Zoology1 and

2. Institute of Virology,2

3. University of Veterinary Medicine, A-1210 Vienna, Schönbrunner Tiergarten Ges.m.b.H., A-1130 Vienna,3 and

4. Department of Medical Parasitology, Clinical Institute of Hygiene, University of Vienna, A-1095 Vienna,4 Austria

Abstract

ABSTRACT In this paper, a serological assay for the detection of antibodies to Capillaria hepatica , a zoonotic parasite, is described. In the past, the only way of detecting Capillaria hepatica was to perform a liver biopsy. The indirect immunofluorescence (IIF) assay, based on liver sections of naturally infected mice and human serum samples, is suitable for detecting early stages of human infections and for screening purposes. No cross-reactivity with other parasitic infections was detected. We have applied the IIF assay to serum samples of 60 employees of the Zoological Garden of Vienna, Schönbrunn, Austria, and found one positive and one questionable sample.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.38.1.431-433.2000

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