Molecular Analysis of Methicillin-Resistant Staphylococcus aureus as a Causative Agent of Bronchopulmonary Infection: Relation to Colonization in the Upper Respiratory Tract

Author:

Watanabe Hiroshi1,Masaki Hironori1,Asoh Norichika1,Watanabe Kiwao1,Oishi Kazunori1,Kobayashi Shinobu2,Sato Akiyoshi3,Nagatake Tsuyoshi1

Affiliation:

1. Department of Internal Medicine, Institute of Tropical Medicine, Nagasaki University,1 and Departments of

2. Internal Medicine2 and

3. Microbiology,3 Kyorin Hospital, Nagasaki, Japan

Abstract

ABSTRACT Using five diagnostic markers, we compared the types of 72 strains of methicillin-resistant Staphylococcus aureus (MRSA) isolated simultaneously from the nasal cavity, pharynx, and sputum from 24 patients. Almost identical MRSA types had colonized the nasal cavity and sputum from the same patient for 21 (88%) of the patients. We speculate that most MRSA organisms isolated in sputum are derived from the nasal cavity, while a few are derived from the pharynx.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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