Characterization of Non-Type B Haemophilus influenzae Strains Isolated from Patients with Invasive Disease-Reference-Cited by-同舟云学术

Characterization of Non-Type B Haemophilus influenzae Strains Isolated from Patients with Invasive Disease

Published:2000-12 Issue:12 Volume:38 Page:4649-4652
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Cerquetti Marina¹,Ciofi degli Atti Marta Luisa²,Renna Giovanna¹,Tozzi Alberto Eugenio²,Garlaschi Maria Laura³,Mastrantonio Paola¹,

Affiliation:

1. Laboratory of Bacteriology and Medical Mycology1 and

2. Laboratory of Epidemiology and Biostatistics,2 Istituto Superiore di Sanità, 00161 Rome, and

3. Azienda Ospedaliera Istituti Clinici di Perfezionamento, 20122 Milan,3 Italy

Abstract

ABSTRACT Forty-one non-type b Haemophilus influenzae isolates from cases of invasive disease were characterized. By PCR capsular genotyping, 33 nonencapsulated strains, 4 type f isolates, and 4 b − strains were identified. By pulsed-field gel electrophoresis, the nonencapsulated isolates exhibited great genetic heterogenicity, whereas the type f and the b − strains seemed to have a clonal spread. Occurrence of the hifA gene was found by PCR in 18% of the nonencapsulated, 50% of the b − , and all of the type f strains. Hemagglutinating fimbriae were generally expressed by nonencapsulated isolates when fimbrial gene hifA was present. Two nonencapsulated isolates not susceptible to ampicillin were detected; no strains were positive for β-lactamase production.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.38.12.4649-4652.2000

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