Lysosomal Enzyme Content of Kupffer and Endothelial Liver Cells Isolated from Germfree and Clean Conventional Rats

Author:

Knook Dick L.1,Barkway Chris1,Sleyster Elisabeth C.1

Affiliation:

1. Institute for Experimental Gerontology TNO, 2280 HV Rijswijk, The Netherlands

Abstract

Rats kept under germfree conditions showed lower specific lysosomal enzyme activities in liver endothelial cells, but not in Kupffer cells.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference20 articles.

1. Radiation-induced life shortening in germfree mice;Anderson R. E.;Exp. Gerontol.,1972

2. The influence of infection on the content of Iysosomal enzymes in rat Kupffer cells and hepatocytes;Berg T.;Acta Pathol. Microbiol. Scand. Sect. A,1976

3. Carbohydrate-mediated clearance of antibody-antigen complexes from the circulation. The role of high mannose oligosaccharides in the hepatic uptake of IgM antigen complexes;Day J. F.;J. Biol. Chem.,1980

4. The Iysosomal enzyme and antibacterial factors in leukocytes, serum and spleens of conventional and germfree piglets;Ferencik M.;Folia Microbiol. (Prague),1979

5. Hepatic clearance of Salmonella typhimurium in silica-treated mice;Friedman R. L.;Infect. Immun.,1977

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