Affiliation:
1. German Federal Institute for Risk Assessment, Berlin, Germany
2. University of Applied Sciences and Arts, Institute for Bioanalysis, Coburg, Germany
Abstract
Foodborne pathogens such as
L. monocytogenes
can persist in food production environments for a long time, causing perennial outbreaks. Hence, bacterial pathogens are able to survive cleaning and disinfection procedures. Accordingly, they may be repeatedly exposed to sublethal concentrations of disinfectants, which might result in bacterial adaptation to these biocides. Furthermore, antibiotic coresistance and cross-resistance are known to evolve under biocide selection pressure
in vitro
. Hence, antimicrobial tolerance seems to play a crucial role in the resilience and persistence of foodborne pathogens in the food chain and might reduce therapeutic options in infectious diseases.
Funder
Federal Institute for Risk Assessment
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology