Effect of an Adenovirus-Vectored Universal Influenza Virus Vaccine on Pulmonary Pathophysiology in a Mouse Model-Reference-Cited by-同舟云学术

Effect of an Adenovirus-Vectored Universal Influenza Virus Vaccine on Pulmonary Pathophysiology in a Mouse Model

Published:2021-04-12 Issue:9 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Dhakal Santosh¹^ORCID,Loube Jeffrey²,Misplon Julia A.³,Lo Chia-Yun³,Creisher Patrick S.¹^ORCID,Mulka Kathleen R.⁴,Deshpande Sharvari¹,Mitzner Wayne²,Klein Sabra L.¹,Epstein Suzanne L.³^ORCID

Affiliation:

1. W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

2. Department of Environmental Health and Engineering, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

3. Division of Cellular and Gene Therapies, Office of Tissues and Advanced Therapies, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA

4. Department of Molecular and Comparative Pathobiology, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA

Abstract

Respiratory viruses can emerge and spread rapidly before vaccines are available. It would be a tremendous advance to use vaccines that protect against whole categories of viruses, such as universal influenza vaccines, without the need to predict which virus will emerge.

Funder

NIH/ORWH/NIA Specialized Center of Research Excellence in Sex Differences

NIH Center of Excellence for Influenza Research and Surveillance

FDA/CBER/DCGT

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.02359-20

Reference64 articles.