Identification of New Compounds against PRRSV Infection by Directly Targeting CD163-Reference-Cited by-同舟云学术

Identification of New Compounds against PRRSV Infection by Directly Targeting CD163

Published:2023-05-31 Issue:5 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Zhu Jiaqi¹^ORCID,He Xin²,Bernard Denzil³,Shen Jianing¹,Su Yue¹,Wolek Andrew¹,Issacs Brianna¹,Mishra Neha⁴,Tian Xiuchun¹,Garmendia Antonio⁴,Tang Young¹²

Affiliation:

1. Department of Animal Science, Institute for Systems Genomics, University of Connecticut, Storrs, Connecticut, USA

2. Shaanxi Centre of Stem Cells Engineering & Technology, Key Laboratory of Livestock Biology, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China

3. Atomwise Inc., San Francisco, California, USA

4. Department of Pathobiology and Veterinary Sciences, University of Connecticut, Storrs, Connecticut, USA

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) causes significant economic losses to the swine industry worldwide. Current vaccines cannot provide cross protection against different strains, and there are no effective treatments available to hamper the spread of this disease.

Funder

U.S. Department of Agriculture

Atomwise Inc. Artificial Intelligence Molecular Screen award

Program In Innovative Therapeutics for Connecticut’s Health Promising Project Award

University of Connecticut Research Excellence Program

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00054-23

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