The Murine Neuronal Receptor NgR1 Is Dispensable for Reovirus Pathogenesis-Reference-Cited by-同舟云学术

The Murine Neuronal Receptor NgR1 Is Dispensable for Reovirus Pathogenesis

Published:2022-04-27 Issue:8 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Aravamudhan Pavithra¹²,Guzman-Cardozo Camila¹²,Urbanek Kelly¹²,Welsh Olivia L.¹²,Konopka-Anstadt Jennifer L.³,Sutherland Danica M.¹²,Dermody Terence S.¹²⁴^ORCID

Affiliation:

1. Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

2. Institute of Infection, Inflammation, and Immunity, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

3. Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA

4. Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Abstract

Viruses engage diverse molecules on host cell surfaces to navigate barriers, gain cell entry, and establish infection. Despite discovery of several reovirus receptors, host factors responsible for reovirus neurotropism are unknown.

Funder

HHS | National Institutes of Health

Pitt | University of Pittsburgh Medical Center | Children's Hospital of Pittsburgh

Heinz Endowments

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00055-22

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1. NgR1 binding to reovirus reveals an unusual bivalent interaction and a new viral attachment protein;Proceedings of the National Academy of Sciences;2023-06-05

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