Abstract
The aerobic, facultative, and anaerobic microorganisms cultivable from the stomachs, ilea, ceca, and colons of BALB/c athymic (nu/nu) mice (normal and wasting), thymus-implanted normal nude mice, and their heterozygous (nu/+) littermates were investigated. Ninety-one species representing 23 genera of bacteria and yeasts were isolated from the 27 mice. The wasting nude mice showed significantly lower numbers of lactobacilli in their stomach microbiota than did mice from the other three groups. The littermate animals appeared unique among the four groups in having corynebacteria as a major constituent of their stomach and ileal flora. The normal nude mice appeared to have a more diverse anaerobic stomach flora than their heterozygous littermates. These minor differences are discussed with respect to possible immunological, physiological, and environmental factors as their cause. Because the gastrointestinal microfloras of the mice from the four groups were not radically divergent from each other, it was concluded that loss of T-cell function does not dramatically alter the makeup of the cultivable gastrointestinal microflora in these mice.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Reference37 articles.
1. Use of anaerobic glove boxes for the cultivation of strictly anaerobic bacteria;Aranki A.;Am. J. Clin. Nutr.,1972
2. Isolation of anaerobic bacteria from human gingiva and mouse cecum by means of a simplified glove box procedure;Aranki A.;Appl. Microbiol.,1969
3. Bailey W. R. and E. G. Scott. 1974. Diagnostic microbiology 4th ed. C. V. Mosby Co. St. Louis.
4. Transparent plastic incubator for the anaerobic glove box;Balish E. B.;Appl. Environ. Microbiol.,1977
5. Buchanan R. E. and N. E. Gibbons (ed.). 1974. Bergey's manual of determinative bacteriology 8th ed. The Williams & Wilkins Co. Baltimore.
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