Discovery of Herpes B Virus-Encoded MicroRNAs-Reference-Cited by-同舟云学术

Discovery of Herpes B Virus-Encoded MicroRNAs

Published:2009-04 Issue:7 Volume:83 Page:3413-3416
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Besecker Michael I.¹,Harden Mallory E.¹,Li Guanglin²,Wang Xiu-Jie²,Griffiths Anthony¹

Affiliation:

1. Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas

2. State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Abstract

ABSTRACT Herpes B virus (BV) naturally infects macaque monkeys and is a close relative of herpes simplex virus. BV can zoonotically infect humans to cause a rapidly ascending encephalitis with ∼80% mortality. Therefore, BV is a serious danger to those who come into contact with these monkeys or their tissues and cells. MicroRNAs are regulators of gene expression, and there have been reports of virus-encoded microRNAs. We hypothesize that BV-encoded microRNAs are important for the regulation of viral and cellular genes. Herein, we report the discovery of three herpes B virus-encoded microRNAs.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.02419-08

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