Sensitivity of Spermidine-Deficient Saccharomyces cerevisiae to Paromomycin

Author:

Balasundaram David1,Tabor Celia White1,Tabor Herbert1

Affiliation:

1. National Institutes of Health, Bethesda, Maryland 20892-0830

Abstract

ABSTRACT Spermidine-deficient Saccharomyces cerevisiae cells are much more sensitive to paromomycin than nondeficient cells, resulting in cessation of growth and cell death.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference9 articles.

1. Spermidine deficiency increases +1 ribosomal frameshifting efficiency and inhibits Ty1 retrotransposition in Saccharomyces cerevisiae.;Balasundaram D.;Proc. Natl. Acad. Sci. USA,1994

2. Spermidine or spermine is essential for the aerobic growth of Saccharomyces cerevisiae.;Balasundaram D.;Proc. Natl. Acad. Sci. USA,1991

3. Cohen S. S. A guide to the polyamines. 1998 Oxford University Press Oxford United Kingdom

4. Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic.;Fourmy D.;Science,1996

5. Hardman J. G. G. Gilman A. Limbird L. L. Goodman & Gilman’s the pharmacological basis of therapeutics 9th ed. 1996 McGraw-Hill Book Co. New York N.Y

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