Epstein-Barr virus infection in carcinoma of the salivary gland

Author:

Raab-Traub N1,Rajadurai P1,Flynn K1,Lanier A P1

Affiliation:

1. Department of Microbiology and Immunology, University of North Carolina, Chapel Hill 27599-7295.

Abstract

Undifferentiated carcinoma of the parotid gland contains clonal Epstein-Barr virus episomes without ladder arrays of restriction enzyme fragments representing virion DNA. Analysis of Epstein-Barr virus transcription in situ in parotid carcinoma specimens revealed that the EBER RNAs, latent membrane protein mRNA, and the BamHI-A rightward reading frame, BARF0, are expressed in the malignant epithelial cells.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference37 articles.

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