Comparative Efficacy of Mayaro Virus-Like Particle Vaccines Produced in Insect or Mammalian Cells

Author:

Abbo Sandra R.1ORCID,Nguyen Wilson2,Abma-Henkens Marleen H. C.1,van de Kamer Denise1,Savelkoul Niek H. A.1,Geertsema Corinne1,Le Thuy T. T.2,Tang Bing2,Yan Kexin2,Dumenil Troy2,van Oers Monique M.1,Suhrbier Andreas23ORCID,Pijlman Gorben P.1ORCID

Affiliation:

1. Laboratory of Virology, Wageningen University & Research, Wageningen, the Netherlands

2. Inflammation Biology Group, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia

3. GVN Center of Excellence, Australian Infectious Disease Research Center, Brisbane, Queensland, Australia

Abstract

Mayaro virus (MAYV) is associated with acute rheumatic disease that can be debilitating and can evolve into months of chronic arthralgia. MAYV is believed to have the potential to emerge as a tropical public health threat, especially if it develops the ability to be efficiently transmitted by urban mosquito vectors, such as Aedes aegypti and/or Aedes albopictus .

Funder

ZonMw

DHAC | National Health and Medical Research Council

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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