Transmission of an Extended-Spectrum-Beta-Lactamase-Producing Escherichia coli (Sequence Type ST131) Strain between a Father and Daughter Resulting in Septic Shock and Emphysematous Pyelonephritis

Author:

Ender Peter T.1,Gajanana Deepakraj2,Johnston Brian3,Clabots Connie3,Tamarkin Frank J.4,Johnson James R.3

Affiliation:

1. Section of Infectious Diseases, St. Luke's Hospital and Health Network, Bethlehem, Pennsylvania

2. Department of Internal Medicine, St. Luke's Hospital and Health Network, Bethlehem, Pennsylvania

3. VA Medical Center, Minneapolis, Minnesota, and Department of Medicine, University of Minnesota, Minneapolis, Minnesota

4. Section of Urology, St. Luke's Hospital and Health Network, Bethlehem, Pennsylvania

Abstract

ABSTRACT Probable transmission of an extended-spectrum-beta-lactamase-producing Escherichia coli strain (sequence type ST131) between a father and daughter was documented. The father developed severe, recurrent pyelonephritis with multiple small abscesses; the daughter later developed septic shock, bacteremia, and extensive emphysematous pyelonephritis. This multidrug-resistant E. coli clone appears to be highly pathogenic and transmissible.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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