Isolation and Properties of Stachyrase A, a Chymotrypsin-Like Serine Proteinase from Stachybotrys chartarum-Reference-Cited by-同舟云学术

Isolation and Properties of Stachyrase A, a Chymotrypsin-Like Serine Proteinase from Stachybotrys chartarum

Published:2002-01 Issue:1 Volume:70 Page:419-421
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Kordula Tomasz¹,Banbula Agnieszka²,Macomson Jeremy³,Travis James²³

Affiliation:

1. Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio 44115

2. Institute of Molecular Biology, Jagiellonian University, 31-120 Cracow, Poland

3. Department of Biochemistry and Molecular Biology, The University of Georgia, Athens, Georgia 30602

Abstract

ABSTRACT A strain of the common mold Stachybotrys chartarum has been isolated from the lung of a child with pulmonary hemorrhage. We report the purification of stachyrase A, a new serine chymotrypsin-like proteinase from S. chartarum . This enzyme cleaves major protease inhibitors, several biologically active peptides, and collagen, all of which are found in the lung.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.70.1.419-421.2002

Reference18 articles.

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3. Elidemir, O., G. N. Colasurdo, S. N. Rossmann, and L. L. Fan. 1999. Isolation of Stachybotrys from the lung of a child with pulmonary hemosiderosis. Pediatrics104:964–966.

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5. Fung, F., R. Clark, and S. Williams. 1998. Stachybotrys, a mycotoxin-producing fungus of increasing toxicologic importance. J. Toxicol. Clin. Toxicol.36:79–86.

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