Affiliation:
1. Department of Microbiology and Immunology, University of Melbourne, Victoria 3010, Australia
Abstract
ABSTRACT
Terminal loss of immune responsiveness in C57BL/10 mice intranasally infected with
Mycobacterium avium
was observed in both spleen and lung. It was nonspecific and related to the duration of infection, not the age of the mice. While there was loss of total T cells, the remaining cells were less efficient at gamma interferon production.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference16 articles.
1. Appelberg, R., R. Soares, P. Ferreira, and M. T. Silva. 1989. Induction of non-specific immunosuppression in mice by mycobacterial infections and its relationship to macrophage activation. Scand. J. Immunol.30:165-174.
2. Barnes, P. F., S. J. Fong, P. J. Brennan, P. E. Twomey, A. Mazumder, and R. L. Modlin. 1990. Local production of tumor necrosis factor and IFN-gamma in tuberculous pleuritis. J. Immunol.145:149-154.
3. Host Defense against
Mycobacterium avium
Does Not Have an Absolute Requirement for Major Histocompatibility Complex Class I-Restricted T Cells
4. Daniel, T. M., M. J. Oxtoby, E. Pinto, and E. Moreno. 1981. The immune spectrum in patients with pulmonary tuberculosis. Am. Rev. Respir. Dis.123:556-559.
5. Fujiwara, H., and I. Tsuyuguchi. 1986. Frequency of tuberculin-reactive T-lymphocytes in pleural fluid and blood from patients with tuberculous pleurisy. Chest89:530-532.
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