Production of Rubratoxin B by Penicillium purpurogenum Stoll-Reference-Cited by-同舟云学术

Production of Rubratoxin B by Penicillium purpurogenum Stoll

Published:1970-04 Issue:4 Volume:19 Page:613-617
ISSN:0003-6919
Container-title:Applied Microbiology
language:en
Short-container-title:Appl Microbiol

Author:

Natori Shinsaku¹²,Sakaki Setsuko¹²,Kurata Hiroshi¹²,Udagawa Shun-Ichi¹²,Ichinoe Masakatsu¹²,Saito Mamoru¹²,Umeda Makoto¹²,Ohtsubo Kohichiro¹²

Affiliation:

1. National Institute of Hygienic Sciences, Kamiyoga-1-chome, Setagaya-ku, Tokyo

2. Institute of Medical Science, the University of Tokyo, Shirokanedai, Minato-ku, Tokyo

Abstract

Culture filtrates and chloroform extracts from Penicillium purpurogenum isolated from foodstuffs were subjected to preliminary survey for toxic effects on HeLa cells and mice. The toxic metabolite was isolated in a crystalline form from P. purpurogenum and was identified as rubratoxin B. Pathological findings observed in HeLa cells and mice treated with the metabolite are briefly described.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://journals.asm.org/doi/pdf/10.1128/am.19.4.613-617.1970

Reference17 articles.

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5. Investigations of the toxic effects in mice of certain species of;Carlton W. W.;Penicillium. Toxicol. Appl. Pharmacol.,1958

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