Role of recent vaccination in production of false-positive coronavirus antibody titers in cats

Author:

Barlough J E,Jacobson R H,Pepper C E,Scott F W

Abstract

Statistical support was obtained for an association between recent vaccination of cats and the presence of elevated background (i.e., anti-cell culture) reactivity in certain of their sera, as detected with a kinetics-based enzyme-linked immunosorbent assay for coronavirus antibodies, implicating routine vaccination as a potential cause of false-positive antibody test results.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference14 articles.

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4. Antibodies to calf serum as a cause of unwanted reaction in immunofluorescence tests;Johansson M. E.;J. Immunol. Methods,1976

5. Enzyme-linked immunosorbent assay for coronaviruses HCV 229E and MHV 3;Kraaijeveld C. A.;J. Gen. Virol.,1980

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