Evaluation of the Performance of Ortho T. cruzi ELISA Test System for the Detection of Antibodies to Trypanosoma cruzi

Author:

Rivera Hilda N.1,McAuliffe Isabel1,Aderohunmu TaLesa12,Wiegand Ryan E.3,Montgomery Susan P.1,Bradbury Richard S.4ORCID,Handali Sukwan1ORCID

Affiliation:

1. Parasitic Diseases Branch, Division of Parasitic Diseases & Malaria, Center for Global Health, Centers for Disease Control & Prevention, Atlanta, Georgia, USA

2. IHRC, Atlanta, Georgia, USA

3. Office of the Director, Division of Parasitic Diseases & Malaria, Center for Global Health, Centers for Disease Control & Prevention, Atlanta, Georgia, USA

4. School of Science, Psychology and Sport, Federation University Australia, Berwick, Australia

Abstract

The serologic diagnosis of chronic Chagas disease, caused by infection with the parasite Trypanosoma cruzi , is challenging and lacks a gold-standard assay. To overcome the problem, CDC uses an algorithm that uses two tests on different platforms and applies a third test as a tiebreaker.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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