Performance of a Novel Low-Cost, Instrument-Free Plasma Separation Device for HIV Viral Load Quantification and Determination of Treatment Failure in People Living with HIV in Malaysia: a Diagnostic Accuracy Study-Reference-Cited by-同舟云学术

Performance of a Novel Low-Cost, Instrument-Free Plasma Separation Device for HIV Viral Load Quantification and Determination of Treatment Failure in People Living with HIV in Malaysia: a Diagnostic Accuracy Study

Published:2019-04 Issue:4 Volume:57 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Pham Minh D.¹²,Haile Berhan A.¹²,Azwa Iskandar³,Kamarulzaman Adeeba³,Raman Nishaan³,Saeidi Alireza⁴,Kahar Bador Maria³,Tan Margaret³,Zhu Jiawei⁵,Feng Yi⁵,Elliott Julian H.²,Garcia Mary L.¹,Li Fan¹,Crowe Suzanne M.¹²,Luchters Stanley¹²⁶⁷,Anderson David A.¹⁵

Affiliation:

1. Burnet Institute, Melbourne, Australia

2. Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia

3. Infectious Disease Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

4. Medical Microbiology Department, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

5. Nanjing BioPoint Diagnostics, Nanjing, People’s Republic of China

6. Department of Population Health, Aga Khan University, Nairobi, Kenya

7. International Centre for Reproductive Health, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium

Abstract

HIV viral load (VL) testing is the recommended method for monitoring the response of people living with HIV and receiving antiretroviral therapy (ART). The availability of standard plasma VL testing in low- and middle-income countries (LMICs), and access to this testing, are limited by the need to use fresh plasma.

Funder

Nanjing BioPoint

Department of Health | National Health and Medical Research Council

Australian Centre for HIV and Hepatitis Virology Research

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01683-18

Reference24 articles.

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2. Impact and Programmatic Implications of Routine Viral Load Monitoring in Swaziland

3. Unnecessary Antiretroviral Treatment Switches and Accumulation of HIV Resistance Mutations; Two Arguments for Viral Load Monitoring in Africa

4. Accumulation of HIV Drug Resistance Mutations in Patients Failing First-Line Antiretroviral Treatment in South Africa

5. Viral Load Monitoring as a Tool to Reinforce Adherence

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