The Intact Retroviral Env Glycoprotein of Human Foamy Virus Is a Trimer-Reference-Cited by-同舟云学术

The Intact Retroviral Env Glycoprotein of Human Foamy Virus Is a Trimer

Published:2000-03-15 Issue:6 Volume:74 Page:2885-2887
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Wilk Thomas¹,de Haas Felix¹,Wagner Andrea²,Rutten Twan¹,Fuller Stephen¹³,Flügel Rolf M.²,Löchelt Martin²

Affiliation:

1. Structural Biology Programme, European Molecular Biology Laboratory, Heidelberg, Germany,1 and

2. Abteilung Retrovirale Genexpression, Forschungsschwerpunkt Angewandte Tumorvirologie, Deutsches Krebsforschungszentrum,2

3. Structural Biology Division, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom3

Abstract

ABSTRACT Electron microscopy of negatively stained human foamy virus particles provides direct evidence for the trimeric nature of intact Env surface glycoproteins. Three-dimensional image reconstruction reveals that the Env trimer is a tapering spike 14 nm in length. The spikes were often arranged in hexagonal rings which shared adjacent Env trimers.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.74.6.2885-2887.2000

Reference16 articles.

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