Targeting Multidrug-Recalcitrant Pseudomonas aeruginosa Biofilms: Combined-Enzyme Treatment Enhances Antibiotic Efficacy-Reference-Cited by-同舟云学术

Targeting Multidrug-Recalcitrant Pseudomonas aeruginosa Biofilms: Combined-Enzyme Treatment Enhances Antibiotic Efficacy

Published:2023-01-24 Issue:1 Volume:67 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Zhang Yixin¹,Wei Wei²,Wen Huamei¹,Cheng Zhongle²,Mi Zhongwen¹,Zhang Jing³^ORCID,Liu Xiaolong⁴,Fan Xinjiong¹^ORCID

Affiliation:

1. School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China

2. The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China

3. Stomatological Hospital and College, Key Laboratory of Oral Diseases Research of Anhui Province, Anhui Medical University, Hefei, Anhui, China

4. University of Science and Technology of China, Hefei, Anhui, China

Abstract

Pseudomonas aeruginosa is an opportunistic pathogen that forms biofilms during infection, resulting in recalcitrance to antibiotic treatment. Biofilm inhibition is a promising research direction for the treatment of biofilm-associated infections.

Funder

Natural Sceince Foundation of Univeristies of Anhui Province

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.01358-22

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