Identification of CD98 as a Novel Biomarker for HIV-1 Permissiveness and Latent Infection-Reference-Cited by-同舟云学术

Identification of CD98 as a Novel Biomarker for HIV-1 Permissiveness and Latent Infection

Published:2022-12-20 Issue:6 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Zhang Wanying¹²,Zhou Mo¹,Chen Cancan³,Wu Shiyu¹,Wang Lilin⁴,Xia Baijin¹,Liu Jun⁵,Ma Xiancai¹^ORCID,Pan Ting¹,Zhang Hui¹^ORCID,Li Linghua²,Liu Bingfeng¹^ORCID

Affiliation:

1. Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China

2. Infectious Diseases Center, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, China

3. Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

4. Shenzhen Blood Center, Shenzhen, Guangdong, China

5. Qianyang Biomedical Research Institute, Guangzhou, Guangdong, China

Abstract

Identification of cellular biomarkers is the crucial challenge to eradicate the HIV-1 latent reservoir. In our study, we identified CD98 as a novel plasma membrane biomarker for HIV-1 permissiveness and latent infection.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Special Research and Development Program of Guangzhou

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02496-22

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