Affiliation:
1. Istituto di Malattie Infettive, Università di Siena, Italy.
Abstract
A total of 66.6% of Campylobacter pylori strains isolated from patients with peptic ulcers produced a cytotoxin active against mammalian cells in vitro, versus 30.1% of strains isolated from patients with chronic gastritis of various degrees of severity only. This difference was statistically significant and suggests that the toxic substance could be involved in the development of peptic ulcers.
Publisher
American Society for Microbiology
Reference3 articles.
1. Campylobacter pyloridis, gastritis, and peptic ulceration;Goodwin C. S.;J. Clin. Microbiol.,1986
2. Cytotoxic activity in broth-culture filtrates of Campylobacter pylori;Leunk R. D.;J. Med. Microbiol.,1988
3. Campylobacter pyloridis degrades mucin and undermines gastric mucosal integrity;Slomiany B. L.;Biochem. Biophys. Res. Commun.,1987
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