Isolation of Group A Streptococci with Reduced In Vitro β-Lactam Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Proteins in Japan-Reference-Cited by-同舟云学术

Isolation of Group A Streptococci with Reduced In Vitro β-Lactam Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Proteins in Japan

Published:2021-11-17 Issue:12 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ikeda Tsubasa¹^ORCID,Suzuki Rihito¹,Jin Wanchun¹,Wachino Jun-ichi¹^ORCID,Arakawa Yoshichika¹,Kimura Kouji¹^ORCID

Affiliation:

1. Department of Bacteriology, Nagoya University Graduate School of Medicine, Nagoya, Japan

Abstract

Streptococcus pyogenes (group A Streptococcus [GAS]) has long been regarded as being susceptible to β-lactams. However, amino acid substitutions in penicillin-binding protein 2X (PBP2X) conferring reduced in vitro β-lactam susceptibility have been indicated since 2019 in the United States and Iceland.

Funder

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01482-21

Reference21 articles.

1. Pathogenesis of Group A Streptococcal Infections

2. β-lactam antibiotics: An overview from a medicinal chemistry perspective

3. Clinical and Laboratory Standards Institute. 2018. Performance standards for antimicrobial susceptibility testing; 28th informational supplement, M100Ed28E. Clinical and Laboratory Standards Institute, Wayne, PA.

4. Have group A streptococci with reduced penicillin susceptibility emerged?

5. First Molecular Characterization of Group B Streptococci with Reduced Penicillin Susceptibility

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