Affiliation:
1. Indian Institute of Experimental Medicine, Calcutta-700032, India
Abstract
Mycobacillin as well as its
O
-acetyl (tyrosyl and seryl) and ester derivatives is known to have antifungal activity. The antibiotic also possesses hemolytic activity. This latter property is not appreciably altered by partial or complete esterification of its free carboxyl groups. On the other hand, acetylation of the molecule at the two tyrosyl hydroxyl groups nullifies selectively the hemolytic activity.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference6 articles.
1. Some preliminary studies on the evaluation of mycobacillin for therapeutic use;Banerjee N.;Bull. Calcutta Sch. Trop. Med.,1959
2. Studies on mycobacillin derivatives. I. Acetyl derivatives of mycobacillin;Banerjee P. C.;J. Antibio.,1973
3. Studies on mycobacillin derivatives: ester derivatives of mycobacillin;Banerjee P. C.;Ind. J. Biochem. Biophys.,1973
4. A quantitative method for the determination of tyrothricin;Dimick K. P.;J. Biol. Chem.,1943
5. Mycobacillin, a new antifungal antibiotic produced by B. subtilis;Majumder S. K.;Nature (London),1958
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