The Coronavirus Infectious Bronchitis Virus Nucleoprotein Localizes to the Nucleolus

Author:

Hiscox Julian A.1,Wurm Torsten1,Wilson Louise1,Britton Paul2,Cavanagh David2,Brooks Gavin1

Affiliation:

1. School of Animal and Microbial Sciences, University of Reading, Reading, Berkshire RG6 6AJ,1 and

2. Division of Molecular Biology, Institute for Animal Health, Compton Laboratory, Compton, Newbury, Berkshire RG20 7NN,2 United Kingdom

Abstract

ABSTRACT The coronavirus nucleoprotein (N) has been reported to be involved in various aspects of virus replication. We examined by confocal microscopy the subcellular localization of the avian infectious bronchitis virus N protein both in the absence and in the context of an infected cell and found that N protein localizes both to the cytoplasmic and nucleolar compartments.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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