Affiliation:
1. Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139
Abstract
ABSTRACT
Initiation of spore formation in
Bacillus subtilis
appears to depend on initiation of DNA replication. This regulation was first identified using a temperature-sensitive mutation in
dnaB
. We found that mutations in the replication initiation genes
dnaA
and
dnaD
also inhibit sporulation, indicating that inhibition of sporulation is triggered by general defects in the function of replication initiation proteins.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
19 articles.
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