Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle-Reference-Cited by-同舟云学术

Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle

Published:2018-10 Issue:10 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Lahlali Thomas¹,Berke Jan Martin²,Vergauwen Karen²,Foca Adrien¹,Vandyck Koen²,Pauwels Frederik²,Zoulim Fabien¹³,Durantel David¹

Affiliation:

1. INSERM, U1052, Cancer Research Center of Lyon, Université de Lyon (UCBL1), CNRS UMR_5286, Centre Léon Bérard, Lyon, France

2. Janssen Research and Development, Beerse, Belgium

3. Liver Unit, Hospices Civils de Lyon, Lyon, France

Abstract

The assembly of hepatitis B virus (HBV) core protein (HBc) into capsids represents a critical step of viral replication. HBc has multiple functions during the HBV life cycle, which makes it an attractive target for antiviral therapies.

Funder

Agence Nationale de la Recherche

Institut National de la Santé et de la Recherche Médicale

Janssen Research and Development

Agence Nationale de Recherches sur le Sida et les Hépatites Virales

Fondation Innovations en Infectiologie

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00835-18

Reference63 articles.

1. Molecular biology of hepatitis B virus infection

2. Effect of Edmonton Symptom Assessment Scale (ESAS) on symptom data collection in a radiation oncology department.

3. Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

4. Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

5. Intracellular transport and egress of hepatitis B virus

Cited by 87 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. THE DUAL-SPECIFICITY KINASE DYRK1A INTERACTS WITH THE HEPATITIS B VIRUS GENOME AND REGULATES THE PRODUCTION OF VIRAL RNA;2024-06-03

2. CAM-A-dependent HBV core aggregation induces apoptosis through ANXA1;JHEP Reports;2024-06

3. Class A capsid assembly modulator apoptotic elimination of hepatocytes with high HBV core antigen level in vivo is dependent on de novo core protein translation;Journal of Virology;2024-03-19

4. Mechanism of interferon alpha therapy for chronic hepatitis B and potential approaches to improve its therapeutic efficacy;Antiviral Research;2024-01

5. Medicinal chemistry strategies in the discovery and optimization of HBV core protein allosteric modulators (2018–2022 update);Chinese Chemical Letters;2023-11