A Grad-seq View of RNA and Protein Complexes in Pseudomonas aeruginosa under Standard and Bacteriophage Predation Conditions

Author:

Gerovac Milan1ORCID,Wicke Laura12ORCID,Chihara Kotaro3,Schneider Cornelius14,Lavigne Rob2ORCID,Vogel Jörg13ORCID

Affiliation:

1. Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany

2. Laboratory of Gene Technology, KU Leuven, Leuven, Belgium

3. Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg, Germany

4. Department of Biochemistry and Cancer Therapy Research Center (CTRC), Theodor Boveri-Institute, University of Würzburg, Würzburg, Germany

Abstract

Stable complexes by cellular proteins and RNA molecules lie at the heart of gene regulation and physiology in any bacterium of interest. It is therefore crucial to globally determine these complexes in order to identify and characterize new molecular players and regulation mechanisms.

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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