A Streptococcus Quorum Sensing System Enables Suppression of Innate Immunity-Reference-Cited by-同舟云学术

A Streptococcus Quorum Sensing System Enables Suppression of Innate Immunity

Published:2021-06-29 Issue:3 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Rahbari Kate M.¹,Chang Jennifer C.²^ORCID,Federle Michael J.²^ORCID

Affiliation:

1. Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois, USA

2. Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, USA

Abstract

Streptococcus pyogenes is restricted to human hosts and commonly causes superficial diseases such as pharyngitis; it can also cause severe and deadly manifestations including necrotizing skin disease or severe postinfectious sequelae like rheumatic heart disease. Understanding the complex mechanisms used by this pathogen to manipulate host defenses could aid in developing new therapeutics to treat infections.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Burroughs Wellcome Fund

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.03400-20

Reference40 articles.

1. Quorum sensing in group A Streptococcus

2. The global burden of group A streptococcal diseases