Consensus on β-Lactamase Nomenclature

Author:

Bradford Patricia A.1ORCID,Bonomo Robert A.2ORCID,Bush Karen3ORCID,Carattoli Alessandra4ORCID,Feldgarden Michael5,Haft Daniel H.5,Ishii Yoshikazu6ORCID,Jacoby George A.7,Klimke William5,Palzkill Timothy8ORCID,Poirel Laurent91011ORCID,Rossolini Gian Maria1213ORCID,Tamma Pranita D.14ORCID,Arias Cesar A.1516ORCID

Affiliation:

1. Antimicrobial Development Specialists LLC, Nyack, New York, USA

2. Cleveland VA, Cleveland, Ohio, USA

3. Indiana University, Bloomington, Indiana, USA

4. Sapienza University of Rome, Rome, Italy

5. The National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA

6. Toho University School of Medicine, Tokyo, Japan

7. Lahey Hospital and Medical Center, Burlington, Massachusetts, USA

8. Baylor College of Medicine, Houston, Texas, USA

9. Emerging Antibiotic Resistance, Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland

10. Swiss National Reference Center for Emerging Antibiotic Resistance, Fribourg, Switzerland

11. INSERM European Unit (LEA), (IAME, Paris) University of Fribourg, Fribourg, Switzerland

12. University of Firenze, Florence, Italy

13. Microbiology and Virology Unit Careggi University Hospital, Florence, Italy

14. Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

15. Division of Infectious Diseases, Houston Methodist Hospital, Houston, Texas, USA

16. Center for Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas, USA

Abstract

Assigning names to β-lactamase variants has been inconsistent and has led to confusion in the published literature. The common availability of whole genome sequencing has resulted in an exponential growth in the number of new β-lactamase genes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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