Interleukin-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenesis- and Tumorigenesis-Promoting Effects-Reference-Cited by-同舟云学术

Interleukin-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenesis- and Tumorigenesis-Promoting Effects

Published:2019-01-15 Issue:2 Volume:39 Page:
ISSN:0270-7306
Container-title:Molecular and Cellular Biology
language:en
Short-container-title:Mol Cell Biol

Author:

Al-Khalaf Huda H.¹²,Al-Harbi Bothaina¹,Al-Sayed Adher³,Arafah Maria⁴,Tulbah Asma⁴,Jarman Abdulaziz⁵,Al-Mohanna Falah⁶,Aboussekhra Abdelilah¹

Affiliation:

1. Department of Molecular Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia

2. The National Center for Stem Cell Technology, King Abdulaziz City for Science and Technology, Riyadh, Kingdom of Saudi Arabia

3. Department of Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia

4. Department of Pathology, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia

5. Department of Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia

6. Department of Comparative Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia

Abstract

Increasing evidence supports the critical role of active stromal adipocytes in breast cancer development and spread. However, the mediators and the mechanisms of action are still elusive.

Funder

King Abdulaziz City for Science and Technology

Publisher

American Society for Microbiology

Subject

Cell Biology,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/MCB.00332-18

Reference47 articles.

1. Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion

2. Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells

3. The fat and the bad: Mature adipocytes, key actors in tumor progression and resistance

4. Leptin signaling in breast cancer: An overview

5. The multifactorial role of leptin in driving the breast cancer microenvironment

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