HemaSpot, a Novel Blood Storage Device for HIV-1 Drug Resistance Testing-Reference-Cited by-同舟云学术

HemaSpot, a Novel Blood Storage Device for HIV-1 Drug Resistance Testing

Published:2016-01 Issue:1 Volume:54 Page:223-225
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Brooks K.¹,DeLong A.²,Balamane M.¹,Schreier L.¹,Orido M.³,Chepkenja M.³,Kemboi E.³,D'Antuono M.¹,Chan P. A.¹,Emonyi W.³⁴,Diero L.³⁴,Coetzer M.¹,Kantor R.¹

Affiliation:

1. Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA

2. Center for Statistical Sciences, School of Public Health, Brown University, Providence, Rhode Island, USA

3. Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya

4. Department of Medicine, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya

Abstract

ABSTRACT HemaSpot, a novel dried-blood storage filter device, was used for HIV-1 pol resistance testing in 30 fresh United States blood samples and 54 previously frozen Kenyan blood samples. Genotyping succeeded in 79% and 58% of samples, respectively, improved with shorter storage and higher viral load, and had good (86%) resistance mutation concordance to plasma.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute on Drug Abuse

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.02853-15

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3. Evaluation of a novel dried blood spot collection device (HemaSpot™) to test blood samples collected from dogs for antibodies to Leishmania infantum

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