Characterizing Risk Factors for Clostridioides difficile Infection among Hospitalized Patients with Community-Acquired Pneumonia

Author:

Rhodes Nathaniel J.123ORCID,Jozefczyk Caroline C.4,Moore W. Justin3,Yarnold Paul R.5,Harkabuz Karolina1,Maxwell Robert3,Sutton Sarah H.67,Silkaitis Christina7,Qi Chao8,Wunderink Richard G.9,Zembower Teresa R.678

Affiliation:

1. Department of Pharmacy Practice, Chicago College of Pharmacy, Midwestern University, Downers Grove, Illinois, USA

2. Pharmacometrics Center of Excellence, Midwestern University, Downers Grove, Illinois, USA

3. Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois, USA

4. Department of Pharmacy, Ohio Health, Mansfield, Ohio, USA

5. Optimal Data Analysis, LLC, Chicago, Illinois, USA

6. Division of Infectious Diseases, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

7. Healthcare Epidemiology and Infection Prevention, Northwestern Medicine, Chicago, Illinois, USA

8. Department of Pathology, Northwestern Memorial Hospital, Chicago, Illinois, USA

9. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

Abstract

Hospitalized patients with community-acquired pneumonia (CAP) are at risk of developing Clostridioides difficile infection (CDI). We developed and tested clinical decision rules for identifying CDI risk in this patient population.

Funder

HHS | NIH | National Center for Advancing Translational Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference51 articles.

1. Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)

2. Centers for Disease Control and Prevention National Center for Health Statistics U.S. Department of Health and Human Services. 2017. Leading causes of death and numbers of deaths by sex race and Hispanic origin: United States 1980 and 2016. https://www.cdc.gov/nchs/data/hus/2017/019.pdf.

3. Chemotherapy in the bacteremia;Finland M;Conn State Med J,1943

4. THE EFFECT OF ANTIBIOTICS (PENICILLIN, AUREOMYCIN, AND TERRAMYCIN) ON THE FATALITY RATE AND INCIDENCE OF COMPLICATIONS IN PNEUMOCOCCIC PNEUMONIA. A COMPARISON WITH OTHER METHODS OF THERAPY

5. Antibiotic resistance threats in the United States, 2019

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