Plasma and Interstitial Fluid Pharmacokinetics of Prophylactic Cefazolin in Elective Bariatric Surgery Patients-Reference-Cited by-同舟云学术

Plasma and Interstitial Fluid Pharmacokinetics of Prophylactic Cefazolin in Elective Bariatric Surgery Patients

Published:2022-07-19 Issue:7 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ryan Rochelle L.¹²³,Jackson Dwane¹³,Hopkins George⁴,Eley Victoria¹³,Christensen Rebecca¹³,Van Zundert Andre A. J.¹³⁵,Wallis Steven C.⁵,Lipman Jeffrey³⁵⁶,Parker Suzanne L.⁵^ORCID,Roberts Jason A.⁵⁶⁷⁸^ORCID

Affiliation:

1. Department of Anaesthesia and Perioperative Medicine, Royal Brisbane and Women’s Hospital, Herston, Queensland, Australia

2. Department of Anaesthesia and Perioperative Medicine, Sunshine Coast University Hospital, Birtinya, Queensland, Australia

3. Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia

4. Department of Surgery, Royal Brisbane and Women’s Hospital, Herston, Queensland, Australia

5. UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia

6. Division of Anaesthesiology Critical Care Emergency and Pain Medicine, Nîmes University Hospital, University of Montpellier, Nîmes, France

7. Department of Intensive Care Medicine, Royal Brisbane and Women’s Hospital, Herston, Queensland, Australia

8. Department of Pharmacy, Royal Brisbane and Women’s Hospital, Herston, Queensland, Australia

Abstract

Guidelines for surgical prophylactic dosing of cefazolin in bariatric surgery vary in terms of recommended dose. This study aimed to describe the plasma and interstitial fluid (ISF) cefazolin pharmacokinetics in patients undergoing bariatric surgery and to determine an optimum dosing regimen.

Funder

Australia and New Zealand College of Anaesthetists Research Foundation

Department of Health | National Health and Medical Research Council

State of Queensland | Advance Queensland

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.00419-22

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